Regional Anesthesia and Acute Pain Medicine: A Problem-Based Learning Approach provides a comprehensive review of regional anesthesia and acute pain medicine for medical learners to integrate theoretical knowledge into clinical practice. Its problem-based format incorporates a pool of multiple-choice questions for self-assessment. Each of its 50 case-based chapters is accompanied by questions and answers accessible online in a full practice exam. These chapters cover several areas such as pharmacology, obstetric and pediatric regional anesthesia, complex acute pain problems, anticoagulation, and regional anesthesia and complicated nerve blocks. The cases presented are also unique, as each chapter starts with a case description, usually a compilation of several actual cases, which branches out through case-based questions to increasingly complex situations. This structure is designed to create an authentic experience mirroring the nuances of a complicated clinical scenario. The discussion sections that follow offer a comprehensive approach to the chapter's subject matter, thus creating a modern, complete, and up-to-date medical review of the topic.