Single-cell Sequencing and Methylation

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

Updating the latest understanding of immune cell functions, cancer progression, infection, and inflammation using single-cell DNA or RNA sequencing

Exploring roles of target gene methylations in the pathogenesis of diseases

Focusing on the clinical applications of single cell sequencing and DNA methylation techniques