Regenerative Medicine - from Protocol to Patient

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.

Volume 1 contains eleven chapters addressing latest basic science knowledge on the 'Biology of Tissue Regeneration'. The principles of cell regeneration control by extracellular matrix and biology of stem cell niches are explained. Depicted are the principles of molecular mechanisms controlling asymmetric cell division, stem cell differentiation, developmental and regenerative biology, epigenetic and genetic control as well as mathematical modelling for cell fate prediction., Regenerative biology of stem cell in the central nervous system, cardiovascular, extremities leading to complex tissue regeneration in the model species axolotl and zebrafish as well as the impact immune signalling on nuclear reprogramming are outlined. The lead experts up to date knowledge gives the reader advanced insight into biological principles of regenerative processes in stem cells, tissues, and organisms.