Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions

This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.

Inhaltsverzeichnis
PART I INTRODUCTION Chapter 1 Epidemiology of Bone Lesions.- Chapter 2 Classification of Primary Bone Lesions.- Chapter 3 General Principles of Bone Pathology.- Chapter 4 Epidemiology of Soft Tissue Lesions.- Chapter 5 Classification of Soft Tissue Lesions.- Chapter 6 General Principle of Soft Tissue Pathology and Molecular Alterations in Musculoskeletal Lesions.- Chapter 7 General Principles of Imaging.- Chapter 8 Staging.- PART II PSEUDOTUMORAL AND BENIGN LESIONS OF BONE Chapter 9 Simple Bone Cyst (Unicameral Bone Cyst).- Chapter 10 Langerhans Cell Histiocytosis.- Chapter 11 Histiocytic Fibroma.- Chapter 12 Fibrous Dysplasia.- Chapter 13 Osteofibrous Dysplasia of Long Bones.- Chapter 14 Desmoid Fibroma (Desmoplastic Fibroma of Bone).- Chapter 15 Chondromas.- Chapter 16 Osteochondromas.- Chapter 17 Chondroblastoma.- Chapter 18 Chondromyxoid Fibroma.- Chapter 19 Osteoid Osteoma.- Chapter 20 Osteoblastoma.- Chapter 21 Aneurysmal Bone Cyst (ABC).- Chapter 22 Giant Cell Tumor.- Chapter 23 Biology of Giant Cell Tumor.- Chapter 24 Other Rare Pseudotumoral Lesions:.- Chapter 25 Other Rare Benign Lesions.- PART III BENIGN LESIONS OF SOFT TISSUES Chapter 26 Myositis Ossificans.- Chapter 27 Pigmented Villonodular Synovitis and Giant Cell Tumor of the Tendon Sheaths (Tenosynovial Giant Cell Tumor).- Chapter 28 Synovial Chondromatosis.- Chapter 29 Fibromatosis (All Types).- Chapter 30 Lipomas.- Chapter 31 Neurofibroma.- Chapter 32 Schwannoma.- Chapter 33 Other Rare Conditions of Pseudotumoral and Benign Lesions of Soft Tissues.- PART IV PRIMARY MALIGNANT TUMORS Chapter 34 Chondrosarcomas (CHS).- Chapter 35 Biology of Conventional Chondrosarcoma.- Chapter 36 Osteosarcomas (OS).- Chapter 37 Biology of Osteosarcomas.- Chapter 38 Chemotherapy of Osteosarcoma.- Chapter 39 Small Blue Round Cell Tumors.- Chapter 40 Biology of Ewing Sarcoma.- Chapter 41 Chemotherapy of Ewing Sarcoma.- Chapter 42 Fibroblastic/Myofibroblastic Tumors.- Chapter 43 Nerve Sheath Tumor.- Chapter 44 Smooth and Striated Muscle.- Chapter 45 Sarcomas with Uncertain Differentiation.- Chapter 46 Vascular Tumors.- Chapter 47 Liposarcomas.- Chapter 48 Chemotherapy of Soft Tissue Sarcomas.- Chapter 49 Adamantinoma.- Chapter 50 Notochordol Differentiation.- Chapter 51 Other Rare Malignant Lesions.- PART V SYSTEMIC LESIONS Chapter 52 Primary Lymphoma of Bone.- Chapter 53 Multiple Myeloma.- Chapter 54 Hodgkins Disease in Bone.- Chapter 55 Metastatic Lesions.